[Vascular endothelium state in different types of antihypertensive treatment]

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en 31 Enero 2015

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Item Type

Journal Article

Title

[Vascular endothelium state in different types of antihypertensive treatment]

Author

Kucherenko, N

Author

Nastradin, O

Author

Eliseeva, E

Author

Potapova, E

Author

Nevzorova, V

Abstract

Aim. To study ozone therapy effects on blood biochemistry (NO metabolites, NOn-), pro-oxidant and antioxidant systems in arterial hypertension (AH) patients. Material and methods. The study was focused on ozone therapy effects on metabolic activity of vascular endothelium and lipid peroxidation (LP) activity in 126 patients with stage I-II AH. The levels of NOn- in serum, malone dialdehyde in plasma and superoxide dismutase in red blood cells were measured. Results. In Stage I-II AH, NOn- concentration was reduced, especially in Stage II AH. After one-month combined treatment, plasma NOn- level was similar to that in controls. As early as after first 7 days, ozone therapy resulted in significant LP activity reduction and increased antioxidant potential (AOP), comparing to standard treatment group. Conclusion. Ozone therapy facilitates normalization of vascular endothelium NO-producing function, decrease in LP activity, and AOP restoration.

Publication

Kardiovaskularnaya terapiya i profilaktika

Volume

8

Issue

1

Pages

29-32

Date

2008

Journal Abbr

Kardiovaskularnaya terapiya i profilaktika

Language

Russian

ISSN

1728-8800

URL

http://elibrary.ru/item.asp?id=9952217

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