Diabetes and chronic oxidative stress. A perspective based on the possible usefulness of ozone therapy

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en 30 Enero 2015

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Item Type

Journal Article

Title

Diabetes and chronic oxidative stress. A perspective based on the possible usefulness of ozone therapy

Author

Bocci, Velio

Author

Zanardi, Iacopo

Author

Huijberts, Maya S.P.

Author

Travagli, Valter

Abstract

It is now well established that hyperglycemia, present in both type 1 and type 2 diabetes, causes a variety of biochemical derangements leading to a diffused vascular damage responsible for several pathologic manifestations. Although preclinical and clinical studies have been performed by an unreliable administration route, the correct approach of oxygen-ozonetherapy may break a vicious circle. Messengers, released by a precise interaction ex vivo of the patient's blood with an equivalent calculated dose of ozone (0.42-0.84 mM), react with a variety of cells after blood infusion and restore a number of functions went astray. This paper aims to open a debate on this new therapy for improving the prognosis of diabetes.

Publication

Diabetes and Metabolic Syndrome: Clinical Research and Reviews

Volume

In Press, Corrected Proof

Date

2010

Journal Abbr

Diabet Metabol Syndrom Clin Res Rev

DOI

10.1016/j.dsx.2010.05.014

ISSN

1871-4021

URL

http://www.sciencedirect.com.ezproxy.uef.fi:2048/science/article/B82Y0-50822FV-1/2/8f315ddd19ef7f07c1f9231c6810cb37

Accessed

2011-02-12 11:27:10

Library Catalog

ScienceDirect

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