05 Febrero 2015
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Item Type

Journal Article

Title

Clinical and microbiological effects of ozone nano-bubble water irrigation as an adjunct to mechanical subgingival debridement in periodontitis patients in a randomized controlled trial

Author

Hayakumo, Sae

Author

Arakawa, Shinichi

Author

Mano, Yoshihiro

Author

Izumi, Yuichi

Abstract

AIM: Ozone nano-bubble water (NBW3) seems to be suitable as an adjunct to periodontal treatment owing to its potent antimicrobial effects, high level of safety, and long storage stability. The aim of the present study was to evaluate the clinical and microbiological effects of NBW3 irrigation as an adjunct to subgingival debridement for periodontal treatment. METHODS: Twenty-two subjects were randomly assigned to one of the two treatment groups: full-mouth mechanical debridement with tap water (WATER) or full-mouth mechanical debridement with NBW3 (NBW3). Clinical examination was performed at baseline and 4 and 8 weeks after treatment. Microbiological examination was carried out just before and after treatment and at 1 and 8 weeks posttreatment. RESULTS: There were significant improvements in all clinical parameters after 4 weeks in both groups. The reduction in the probing pocket depth and the clinical attachment gain after 4 and 8 weeks in the NBW3 group were significantly greater than those in the WATER group. Moreover, only the NBW3 group showed statistically significant reductions in the mean total number of bacteria in subgingival plaque over the study period. CONCLUSIONS: The present study suggests that subgingival irrigation with NBW3 may be a valuable adjunct to periodontal treatment. CLINICAL RELEVANCE: This study verified the potential of new antimicrobial agent, MNW3, as an adjunct to periodontal treatment.

Publication

Clinical Oral Investigations

Date

Mar 17, 2012

DOI

10.1007/s00784-012-0711-7

ISSN

1436-3771

URL

http://www.ncbi.nlm.nih.gov/pubmed/22422082

Accessed

2012-03-17 10:22:54

Library Catalog

NCBI PubMed

Extra

PMID: 22422082

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05 Febrero 2015
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Item Type

Conference Paper

Title

Clinical Applications and Research of Ozone in Dentistry

Author

T Weiser, Mark

Author

Martinez Abreu, Judit

Date

2011/ 10 / 7

Conference Name

III. Iberoamerican Congress of Oxygen- Ozonetherapy. II. Brazilian Congress of Ozonetherapy. I. Brazilian Congress of Hydro- Ozonetherapy

Place

Rio de Janeiro (Brazil)

Language

English

URL

 

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05 Febrero 2015
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Item Type

Journal Article

Title

[Clinical applications of ozone in dentistry]

Author

de Oliveira, André Frutuoso

Author

Mendes, Haroldo José

Abstract

The ozone is an allotropic form of oxygen whose unique properties offer a wide application to biological systems and clinical treatments. Although discovered in the year 1840, its clinical use is current, finding applicability in various specialties in the dentistry pratice. This article aims to review the clinical applications of ozone in various dental specialties. The compound provides a high purifying capacity, responsible for microbicides actions (bacteria, fungi and viruses), through oxidation mechanisms not yet elucidated, makes it an alternative against the diseases. In dentistry practice, the ozone can be employed in process of sterilization of instruments and purification system of irrigation to dental unit, serving as a good strategy in the control and prevention of crossinfection in the dental environment. However, the administration of ozone at low concentration by systemic way induces tissue proliferation and neovascularization, and thus inducing a healing, a characteristic that makes it attractive from the clinical, as it allows both the elimination of bacteria such as the repair of anatomical structures. It has limited use in treating endodontic infections and tooth decay. The ozone can be used in the treatment of various oral diseases, reducing the clinical course of disease, achieving superior results in comparison to conventional therapies. Despite the literature showing positive results with the use of ozone in cariology, surgery, periodontics and endodontics, there is need for further studies with standardized methodologies to reach a definitive conclusion about its applicability. Key words: ozone, dentistry, microbiology, pharmacology.

Publication

Revista Saúde.com

Volume

5

Issue

2

Pages

128-140

Date

2009

Journal Abbr

Rev Saúde.com

Language

Portuguese

ISSN

1809-0761 (online)

URL

http://www.uesb.br/revista/rsc/

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