23 Enero 2015
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Item Type

Journal Article

Title

Infiltración terapéutica intra-prostática con Ozono / Oxígeno. Estudio preliminar

Author

Barbod, A

Author

Boada, J

Author

Faus-Vitoria, J.

Author

Benages, J

Author

González, P

Abstract

The objective was a preliminary approach to the use of ozone in different prostatic pathologies. Prostatic diseases coexist both in middle aged and in older patients. The study was carried out right after the injection of ozone/oxygen gas, into the prostate to those patients that have been diagnosed with prostatic disease and checked with a biopsy. The initial hypothesis was that O3 protect patients against side effects as infection or bleeding, due to its scleroses and fungicide properties. The procedure, echo-directed, took place by inserting a transrectal ultrasonic probe while injecting O3 manually, using a Chiva needle 23G x 178 cm. The study and a follow up involve 25 patients. The results do not show any objective benefit in cancer or Benign Prostate Hyperplasia (BPH). Nevertheless, satisfactory evolution was show in chronic prostatitis where was noticed a mitigation of symptoms during the follow-up. The biological properties of ozone and its initial results in its applications in chronic prostatitis can be useful to extend and confirm the benefits observed in this pathology which frequently resist to conventional treatments and became a serious problem. Valuable effects in BPH or cancer remain excluded of this procedure

Publication

Revista Española de Ozonoterapia

Volume

3

Issue

1

Pages

45-53

Date

2013

Language

Spanish

URL

http://www.revistaespañoladeozonoterapia.es/index.php/reo/article/view/37/40

Extra

El objetivo del trabajo fue valorar, con fines terapéuticos, el comportamiento de la glándula prostática en sus diferentes patologías presentes en grupos de edad media y avanzada, tras la aplicación de gas médico, ozono / oxígeno, en punción directa intra-prostática a pacientes con indicación de biopsia prostática. Se partió de la hipótesis de que la aplicación de O3 utilizado al término de la biopsia, puede proteger al paciente de efectos secundarios como el sangrado y la infección, por su capacidad esclerosante vascular y germicida. El procedimiento, eco-dirigido, se efectuó mediante una sonda ultrasónica transrectal e inyección manual intra-prostática de O3, en tiempo real, utilizando una aguja Chiva 23G x 178 cm. En el estudio participaron 25 pacientes. Los resultados no aportan beneficios objetivables en pacientes con hiperplasia prostática benigna (HPB) ni en el cáncer, sin embargo mejoraron los casos de prostatitis crónicas donde se observó una disminución de la sintomatología, en los controles evolutivos. Las propiedades biológicas del ozono y los resultados iniciales de su aplicación en las prostatitis crónicas, puede ser un camino para ampliar y confirmar los beneficios obtenidos en esta patología cuya resistencia, en ocasiones, a los tratamientos convencionales es un problema todavía sin resolver. Desestimamos efectos de interés, en el cáncer o la HPB, a través de este procedimiento.

 

 

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23 Enero 2015
Administrator

Added by

gregorcuba

Item Type

Journal Article

Title

Fistula function and dialysis adequacy during ozonotherapy in chronically hemodialyzed patients

Author

Tylicki, Leszek

Author

Biedunkiewicz, Bogdan

Author

Nieweglowski, Tomasz

Author

Grabowska, Malgorzata

Author

Chamienia, Andrzej

Author

Slizien, Alicja Debska

Author

Rutkowski, Boleslaw

Abstract

There are a variety of complications related to chronic hemodialysis treatment, including thrombosis in hemodialysis access leading to blood recirculation, and in turn to the deterioration in hemodialysis effectiveness. Given that ozone decreases blood viscosity, increases erythrocyte deformability, and inhibits coagulation, the periodic blood ozonation may be of benefit in the attenuation of these disturbances. To gain insight into this issue,we originally evaluated the impact of ozonated autohemotherapy on recirculation in arteriovenous fistula, hemodialysis adequacy, and the frequency of dialyzer reuse. Twelve chronically hemodialyzed patients with peripheral arterial disease were enrolled in the prospective, placebo-controlled study. Nine sessions of autohemotherapy with the exposure of blood to oxygen, as a control, and nine sessions of autohemotherapy where the blood is exposed to ozone in a concentration of 50 microg/mL are administered in a single-blind manner. Access recirculation is measured by means of spectral technology(Crit Line Monitor, HemaMetrics, Kaysville, UT, U.S.A.), and hemodialysis adequacy is calculated using the Daugirdas formula and expressed as the Kt/V index. The Kt/V index and the frequency of dialyzer reuse do not change after ozonated autohemotherapy. Recirculation decreases after ozonotherapy in the majority of patients.on average by 35.3%, but the change does not reach the level of statistical significance (P = 0.064). We demonstrate that ozonated autohemotherapy does not influence dialysis adequacy and the frequency of dialyzer reuse. The improvement of fistula function, expressed as a decrease in recirculation, is not significant, although seen in the majority of patients.

Publication

Artificial Organs

Volume

28

Issue

5

Pages

513-517

Date

May 2004

Journal Abbr

Artif Organs

ISSN

0160-564X

URL

http://www.ncbi.nlm.nih.gov/pubmed/15156869

Accessed

2010-02-24 16:41:37

Library Catalog

NCBI PubMed

Extra

PMID: 15156869

 

 

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23 Enero 2015
Administrator

Added by

gregorcuba

Item Type

Journal Article

Title

Blood coagulation unaffected by ozonated autohemotherapy in patients on maintenance hemodialysis

Author

Biedunkiewicz, Bogdan

Author

Lizakowski, Slawomir

Author

Tylicki, Leszek

Author

Skiboeska, Anna

Author

Nieweglowski, Tomas

Author

Chamienia, Andrzej

Author

Debska-Slizien, Alicja

Author

Rutkowski, Boleslaw

Abstract

BACKGROUND: Ozonated autohemotherapy (O(3)-AHT) is a clinically useful therapeutic procedure in hemodialyzed patients with peripheral arterial occlusive disease (PAOD). The majority of patients on dialysis are in a hypercoagulable state. Thrombotic complications are the major cause of morbidity and mortality in hemodialyzed patients. Effects of O(3)-AHT on blood coagulation were evaluated in 11 hemodialyzed patients affected by PAOD. METHODS: We performed an oxygen-controlled, crossover study in which nine sessions of autohemotherapy with oxygen administration (AHT) as a control were followed by nine sessions of O(3)-AHT. Blood coagulation was assessed by antithrombin III, activated partial thromboplastin time, prothrombin time, D-dimer and fibrinogen plasma concentrations. RESULTS: The extents of all the measured parameters after nine sessions of O(3)-AHT did not differ statistically from the values after nine sessions of AHT. Similarly, there were no differences in the measured variables after the first session of O(3)-AHT as compared to the values before therapy. We did not observe any thrombotic accidents during the study. CONCLUSIONS: O(3)-AHT with ozone concentration of 50 microg/mL and citrate as an anticoagulant does not influence blood coagualation parameters in hemodialyzed patients with PAOD.

Publication

Archives of Medical Research

Volume

37

Issue

8

Pages

1034-1037

Date

Nov 2006

Journal Abbr

Arch. Med. Res

DOI

10.1016/j.arcmed.2006.06.006

ISSN

0188-4409

URL

http://www.ncbi.nlm.nih.gov/pubmed/17045123

Accessed

2010-02-24 16:39:22

Library Catalog

NCBI PubMed

 

 

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